Square Maths Brain Teaser with Answer

In this Square Maths Brain Teaser, there are four number grouped in a Square. These numbers are bound to each other with some Maths Logic or Pattern. Can you find this Maths pattern which is used to group these numbers and then find the value of the missing number which will replace the question mark?
Maths Brain Teaser to find the missing Number
Can you find the missing number?

Answer can be viewed by clicking on button. Please do give your best try before looking at the answer.

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